Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786990 | 0.81 | MAPT (0.42) | MEN1MAPTKMT2ANPSR1TSHR | |
| SCHEMBL71630 | 0.78 | — | — | |
| SCHEMBL3793543 | 0.76 | ALDH1A1 (0.38) | MEN1MAPTKMT2ATSHRALDH1A1 | |
| SCHEMBL19631398 | 0.76 | ALDH1A1 (0.34) | MEN1KMT2ATSHRALDH1A1NR4A2 | |
| SCHEMBL3791972 | 0.76 | DHFR (0.44) | MEN1MAPTKMT2ATSHRALDH1A1 | |
| SCHEMBL3804192 | 0.75 | TSHR (0.50) | MEN1KMT2ATSHRALDH1A1NR4A2 | |
| Hydrochloric Acid SCHEMBL29274502 | 0.75 | TSHR (0.50) | MEN1KMT2ATSHRALDH1A1NR4A2 | |
| SCHEMBL3550151 | 0.74 | MEN1 (0.62) | MEN1MAPTKMT2ANPSR1APOBEC3G | |
| SCHEMBL943125 | 0.74 | TSHR (0.46) | MEN1MAPTKMT2ANPSR1APOBEC3G | |
| SCHEMBL225608 | 0.73 | FBP1 (0.55) | MEN1MAPTKMT2ANPSR1APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337357-A | 1,4-BENZOTHIAZINE INTERMEDIATES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-06-29 | — | — | US | disclosed |
| US-4268301-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-05-19 | — | — | US | disclosed |