Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11284128 | 0.89 | HTR7 (0.59) | HTR7ABCB1HTR2ADRD2DRD1 | |
| SCHEMBL11276314 | 0.87 | HTR7 (0.59) | HTR7ABCB1HTR2ADRD2DRD1 | |
| SCHEMBL11299358 | 0.85 | HTR7 (0.59) | HTR7ABCB1DRD2DRD1DRD3 | |
| SCHEMBL11266553 | 0.85 | HTR1A (0.62) | HTR7HTR2ADRD2DRD3SIGMAR1 | |
| SCHEMBL11814714 | 0.85 | HTR7 (0.57) | HTR7ABCB1HTR2ADRD2DRD1 | |
| SCHEMBL11280944 | 0.84 | HTR7 (0.60) | HTR7ABCB1DRD2DRD1DRD3 | |
| SCHEMBL11262793 | 0.84 | RECQL (0.66) | HTR7HTR2ADRD2SIGMAR1 | |
| SCHEMBL11273822 | 0.81 | DRD2 (0.53) | HTR7ABCB1HTR2ADRD2DRD1 | |
| SCHEMBL11285131 | 0.81 | DRD2 (0.69) | HTR7HTR2ADRD2SIGMAR1 | |
| SCHEMBL11269670 | 0.81 | HTR2A (0.55) | HTR7HTR2ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339580-A | TRANQUILIZERS, SEDATIVES | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1982-07-13 | — | — | US | disclosed |
| EP-0021368-B1 | PIPERAZINYLALKOXYINDANES AND ACID ADDITION SALTS THEREOF | MITSUBISHI KASEI CORPORATION (JP) | 1982-05-19 | — | — | EP | disclosed |
| EP-0021368-A1 | Piperazinylalkoxyindanes and acid addition salts thereof | MITSUBISHI KASEI CORPORATION (JP) | 1981-01-07 | — | — | EP | disclosed |