SCHEMBL11262830

SCHEMBL11262830

O=S(=O)(Cc1ccccc1)c1nc[nH]n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.47
FAAH O00519 1/20 0.46
PRSS1 P07477 1/20 0.46
PRSS2 P07478 1/20 0.46
ELANE P08246 1/20 0.46
PRTN3 P24158 1/20 0.46
PRSS3 P35030 1/20 0.46
MAPT P10636 3/20 0.44
ALDH1A1 P00352 2/20 0.44
LMNA P02545 1/20 0.44
HPGD P15428 1/20 0.44
HTT P42858 1/20 0.44
XDH P47989 1/20 0.41
POLB P06746 1/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA5A P35218 1/20 0.41
CA9 Q16790 1/20 0.41
KMT2A Q03164 2/20 0.41
TSHR P16473 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14027401 0.83 MEN1 (0.44) MAPTALDH1A1LMNAHPGDHTT
SCHEMBL14027280 0.82 TP53 (0.44) MAPTALDH1A1LMNAKMT2ASMN1; SMN2
SCHEMBL14027398 0.78 AKR1B1 (0.57) AKR1B1LMNA
SCHEMBL10728701 0.76 ALDH1A1 (0.50) AKR1B1FAAHPRSS1PRSS2ELANE
SCHEMBL9618200 0.76 KEAP1 (0.53) MAPTALDH1A1LMNAPOLBCA1
SCHEMBL28347450 0.76 ALDH1A1 (0.48) ALDH1A1POLBCA2KMT2AMEN1
SCHEMBL9435542 0.73 HTR6 (0.48) AKR1B1ALDH1A1CA1CA2CA5A
SCHEMBL14027275 0.70 KDM4E (0.57) AKR1B1MAPTALDH1A1LMNAHPGD
SCHEMBL10973040 0.70 MAPT (0.52) FAAHPRSS1PRSS2ELANEPRTN3
SCHEMBL10972259 0.70 MAPT (0.49) AKR1B1FAAHPRSS1PRSS2ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4363915-A PRE-EMERGENT GULF OIL CORPORATION (US) 1982-12-14 US disclosed
EP-0045566-A2 Benzylsulfonyl diethylcarbamyl triazole and use as a selective herbicide Gulf Oil Corporation (US) 1982-02-10 EP disclosed
US-4280831-A Benzylsulfonyl diethylcarbamyl triazole and use as a selective herbicide GULF OIL CORPORATION (US) 1981-07-28 US disclosed