Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 4/20 | 0.40 |
| ▸ | ATP4A | P20648 | 1/20 | 0.37 |
| ▸ | ATP4B | P51164 | 1/20 | 0.37 |
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270501 | 0.92 | HMOX1 (0.45) | HMOX1NOS1ATP4AATP4BQPCT | |
| SCHEMBL11261555 | 0.91 | KMT2A (0.40) | HMOX1QPCTCYP3A4CYP1A2CYP2D6 | |
| SCHEMBL11261792 | 0.90 | NOS1 (0.44) | HMOX1NOS1ATP4AATP4BQPCT | |
| SCHEMBL11250126 | 0.90 | HMOX1 (0.38) | HMOX1NOS1ATP4AATP4BQPCT | |
| SCHEMBL11252110 | 0.89 | HMOX1 (0.43) | HMOX1NOS1ATP4AATP4BQPCT | |
| SCHEMBL11262886 | 0.88 | CYP19A1 (0.41) | QPCT | |
| SCHEMBL11266390 | 0.87 | HMOX1 (0.42) | HMOX1NOS1 | |
| SCHEMBL11262771 | 0.87 | CYP1A2 (0.39) | HMOX1QPCTCYP3A4CYP1A2CYP2D6 | |
| SCHEMBL11267828 | 0.86 | MEN1 (0.42) | QPCTCYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11258691 | 0.85 | NOS1 (0.44) | HMOX1NOS1ATP4AATP4BQPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |