Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NSD2 | O96028 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11439308 | 0.83 | CXCL8 (0.46) | ALDH1A1L3MBTL1CXCL8AKR1C3AKR1C2 | |
| SCHEMBL11251904 | 0.83 | CXCL8 (0.35) | CXCL8AKR1C3AKR1C2PTGS2ALOX5 | |
| SCHEMBL11266224 | 0.81 | CXCL8 (0.41) | ALDH1A1MAPTEGFRMAPK1TDP1 | |
| SCHEMBL11257643 | 0.80 | PSEN1 (0.39) | CNR2ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL11254442 | 0.78 | KDM4E (0.38) | ALDH1A1MAPTTP53SMN1; SMN2KDM4E | |
| SCHEMBL11249334 | 0.77 | TDP1 (0.44) | CNR2MAPTTDP1SLC40A1PTGS2 | |
| SCHEMBL11256929 | 0.75 | RAB9A (0.40) | ALDH1A1MAPTLMNAMAPK1L3MBTL1 | |
| SCHEMBL11257836 | 0.74 | BCHE (0.41) | MAPTAKR1C3AKR1C2PTGS2MMP1 | |
| SCHEMBL11259590 | 0.74 | TRPV1 (0.37) | ALDH1A1CXCL8PTGS2MMP1MMP2 | |
| SCHEMBL11255431 | 0.74 | SELPLG (0.44) | LMNACXCL8MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |