Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALPL | P05186 | 2/20 | 0.54 |
| ▸ | ALPI | P09923 | 2/20 | 0.54 |
| ▸ | ALPG | P10696 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10903296 | 0.83 | KMT2A (0.67) | KMT2AALPLALPIALPGMEN1 | |
| SCHEMBL11259450 | 0.76 | MEN1 (0.52) | KMT2AMEN1GAAHPGDALDH1A1 | |
| SCHEMBL10414788 | 0.76 | ALDH1A1 (0.59) | KMT2AALPLALPIALPGMEN1 | |
| SCHEMBL10964144 | 0.76 | KMT2A (0.57) | KMT2AALPLALPIALPGMEN1 | |
| SCHEMBL11266771 | 0.74 | ALDH1A1 (0.56) | KMT2AMEN1GAAMAPTPOLB | |
| SCHEMBL2858346 | 0.73 | PKM (0.63) | KMT2AALPLALPIALPGMEN1 | |
| SCHEMBL9344656 | 0.72 | ALDH1A1 (0.72) | KMT2AALPLALPIALPGMEN1 | |
| SCHEMBL11718062 | 0.72 | THRB (0.51) | KMT2AMEN1HPGDMAPTPOLB | |
| Hydrochloric Acid SCHEMBL10955756 | 0.72 | PKM (0.61) | KMT2AALPLALPIALPGMEN1 | |
| SCHEMBL6186553 | 0.71 | KMT2A (0.56) | KMT2AALPLALPIALPGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329363-A | Substituted mercapto acid amides and their use | MERCK & CO., INC. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4216160-A | IMMUNOREGULANTS FOR CORRECTING AN INBALANCE OF IMMUNE HOMEOSTASIS | MERCK & CO., INC. (US) | 1980-08-05 | — | — | US | disclosed |