SCHEMBL11263534

SCHEMBL11263534

CN1CC(=N)N(c2cccc(C(C)(C)C)c2)C1=O

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
PIK3CA P42336 7/20 0.36
MTOR P42345 7/20 0.36
CTSK P43235 1/20 0.36
AR P10275 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HSP90AA1 P07900 1/20 0.34
MGLL Q99685 1/20 0.34
ACHE P22303 1/20 0.34
ELANE P08246 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11302984 0.82 DRD2 (0.39) KMT2AELANE
SCHEMBL11267668 0.81 KMT2A (0.49) MEN1KMT2AHSP90AA1MGLL
SCHEMBL11037007 0.78 MGLL (0.41) MEN1KMT2AMGLLELANE
SCHEMBL10876515 0.77 DRD2 (0.44) NOTUMHDAC4HDAC2HDAC8L3MBTL1
SCHEMBL32675950 0.74 MEN1 (0.52) NOTUMHDAC4HDAC2HDAC8L3MBTL1
SCHEMBL10874837 0.74 PIM1 (0.39) PIK3CAMTORMGLL
SCHEMBL11278353 0.74 MEN1 (0.56) PIK3CAMTORARMEN1KMT2A
SCHEMBL14632229 0.72 DRD2 (0.46) NOTUMHDAC4HDAC2HDAC8MEN1
SCHEMBL10874965 0.72 KMT2A (0.47) MEN1KMT2A
SCHEMBL10875869 0.72 RAD51 (0.37) ARMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0024570-B1 5-IMINO-IMIDAZOLINE-2-ONES, HERBICIDES CONTAINING THEM AND PROCESS FOR DESTRUCTING UNDESIRED PLANTS BASF Aktiengesellschaft (DE) 1982-05-12 EP disclosed
EP-0024570-A1 5-Imino-imidazoline-2-ones, herbicides containing them and process for destructing undesired plants BASF Aktiengesellschaft (DE) 1981-03-11 EP disclosed