SCHEMBL11267668

SCHEMBL11267668

CN1CC(=N)N(c2cccc(Cl)c2)C1=O

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.49
MEN1 O00255 4/20 0.49
MGLL Q99685 1/20 0.49
GAA P10253 3/20 0.47
MAPT P10636 3/20 0.45
ALDH1A1 P00352 3/20 0.45
TSHR P16473 1/20 0.45
HTT P42858 1/20 0.45
BCL2A1 Q16548 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CASP6 P55212 1/20 0.41
HSP90AA1 P07900 1/20 0.41
KDM4E B2RXH2 1/20 0.40
DRD2 P14416 1/20 0.40
DRD3 P35462 1/20 0.40
KCNH2 Q12809 1/20 0.40
PGR P06401 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10508406 0.84 KMT2A (0.55) KMT2AMEN1MGLLGAAMAPT
SCHEMBL11278830 0.83 TSHR (0.43) ALDH1A1TSHRBCL2A1SMN1; SMN2KDM4E
SCHEMBL11270496 0.82 ELANE (0.44) KMT2AMEN1MGLLMAPTALDH1A1
SCHEMBL11037007 0.82 MGLL (0.41) KMT2AMEN1MGLLGAAALDH1A1
SCHEMBL10874965 0.81 KMT2A (0.47) KMT2AMEN1MAPTALDH1A1BCL2A1
SCHEMBL11276928 0.81 KMT2A (0.50) KMT2AMEN1GAAMAPTALDH1A1
SCHEMBL10876515 0.81 DRD2 (0.44) MGLLMAPTALDH1A1HTTSMN1; SMN2
SCHEMBL11263534 0.81 NOTUM (0.37) KMT2AMEN1MGLLHSP90AA1
SCHEMBL11268915 0.80 ALDH1A1 (0.54) KMT2AMEN1GAAMAPTALDH1A1
SCHEMBL10875869 0.78 RAD51 (0.37) KMT2AMEN1GAAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0024570-B1 5-IMINO-IMIDAZOLINE-2-ONES, HERBICIDES CONTAINING THEM AND PROCESS FOR DESTRUCTING UNDESIRED PLANTS BASF Aktiengesellschaft (DE) 1982-05-12 EP disclosed
EP-0024570-A1 5-Imino-imidazoline-2-ones, herbicides containing them and process for destructing undesired plants BASF Aktiengesellschaft (DE) 1981-03-11 EP disclosed