SCHEMBL11037007

SCHEMBL11037007

CN1CC(=N)N(c2ccccc2)C1=O

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.41
ALDH1A1 P00352 3/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
GAA P10253 1/20 0.39
GSK3A P49840 1/20 0.38
GSK3B P49841 1/20 0.38
ELANE P08246 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
PLA2G7 Q13093 1/20 0.37
HPGD P15428 1/20 0.37
ENPP2 Q13822 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11270496 0.82 ELANE (0.44) MGLLALDH1A1MEN1KMT2AGSK3A
SCHEMBL11267668 0.82 KMT2A (0.49) MGLLALDH1A1MEN1KMT2AGAA
SCHEMBL11276548 0.81 ENPP2 (0.49) MGLLALDH1A1MEN1KMT2ANPC1
SCHEMBL11269762 0.80 MGLL (0.50) MGLLALDH1A1MEN1KMT2ANPC1
SCHEMBL10876723 0.80 MGLL (0.50) MGLLALDH1A1MEN1KMT2ANPSR1
SCHEMBL11302984 0.80 DRD2 (0.39) ALDH1A1KMT2AELANENPSR1HPGD
SCHEMBL11263534 0.78 NOTUM (0.37) MGLLMEN1KMT2AELANE
SCHEMBL10876515 0.78 DRD2 (0.44) MGLLALDH1A1ELANEHPGD
SCHEMBL6365262 0.78 ALDH1A1 (0.42) MGLLALDH1A1MEN1KMT2ANPC1
SCHEMBL11278830 0.76 TSHR (0.43) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59167572-A None JP disclosed
JP-S59167572-A IMIDAZOLIDIN-2-ONE DERIVATIVE OTSUKA CHEM CO LTD 1984-09-21 JP disclosed
EP-0024570-B1 5-IMINO-IMIDAZOLINE-2-ONES, HERBICIDES CONTAINING THEM AND PROCESS FOR DESTRUCTING UNDESIRED PLANTS BASF Aktiengesellschaft (DE) 1982-05-12 EP disclosed
EP-0024570-A1 5-Imino-imidazoline-2-ones, herbicides containing them and process for destructing undesired plants BASF Aktiengesellschaft (DE) 1981-03-11 EP disclosed