Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 3/20 | 0.38 |
| ▸ | FNTB | P49356 | 3/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269138 | 0.88 | TSHR (0.42) | LMNACYP19A1 | |
| SCHEMBL11269111 | 0.88 | ADRA2C (0.41) | LMNAFNTAFNTBPGGT1BCYP2C9 | |
| SCHEMBL11274130 | 0.84 | FNTA (0.41) | MAPTLMNAKMT2AFNTAFNTB | |
| SCHEMBL11252157 | 0.83 | FNTA (0.38) | MAPTLMNAKMT2AFNTAFNTB | |
| SCHEMBL11251801 | 0.82 | HMOX1 (0.40) | LMNAFNTAFNTBPGGT1BCYP2C9 | |
| SCHEMBL11261952 | 0.81 | FNTA (0.40) | MAPTLMNAKMT2AFNTAFNTB | |
| SCHEMBL11270007 | 0.81 | MAPK1 (0.36) | MAPTLMNAKMT2ACYP19A1 | |
| SCHEMBL11258579 | 0.80 | CYP2C9 (0.44) | MAPTLMNAKMT2AFNTAFNTB | |
| SCHEMBL11266073 | 0.80 | CYP2A6 (0.45) | CYP19A1 | |
| SCHEMBL11273188 | 0.80 | QPCT (0.43) | LMNACYP19A1TBXAS1SMN1; SMN2QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |