Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.45 |
| ▸ | HMOX1 | P09601 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11255295 | 0.90 | CYP19A1 (0.45) | CYP19A1CYP11B1CYP11B2KDM4E | |
| SCHEMBL11266807 | 0.89 | HMOX1 (0.45) | CYP19A1CYP11B1CYP11B2HMOX1KDM4E | |
| SCHEMBL11257241 | 0.89 | CYP2A6 (0.47) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 | |
| SCHEMBL11261696 | 0.89 | TBXAS1 (0.42) | CYP19A1CYP11B1CYP11B2HMOX1 | |
| SCHEMBL11257432 | 0.89 | CYP2A6 (0.47) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 | |
| SCHEMBL11258901 | 0.87 | CYP2A6 (0.43) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 | |
| SCHEMBL11253700 | 0.87 | KMT2A (0.43) | CYP19A1HMOX1KDM4ETP53 | |
| SCHEMBL11258234 | 0.87 | MEN1 (0.45) | CYP19A1CYP11B1KDM4ETP53TSHR | |
| SCHEMBL11265140 | 0.86 | NOS1 (0.46) | CYP19A1HMOX1KDM4ETP53 | |
| SCHEMBL11255906 | 0.86 | CYP2A6 (0.46) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |