Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27502838 | 0.90 | NPC1 (0.53) | HDAC8HDAC6HDAC2HDAC1TDP1 | |
| SCHEMBL11262828 | 0.86 | NPC1 (0.48) | HDAC8HDAC6HDAC2HDAC1L3MBTL1 | |
| SCHEMBL14268630 | 0.78 | KMT2A (0.50) | HDAC8HDAC6HDAC2HDAC1TDP1 | |
| SCHEMBL30984376 | 0.78 | ALDH1A1 (0.56) | HDAC6HDAC1L3MBTL1TDP1MEN1 | |
| SCHEMBL23181449 | 0.78 | BCHE (0.47) | L3MBTL1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL23181168 | 0.76 | TACR1 (0.54) | HDAC8HDAC6RAB9ANPC1KCNK3 | |
| SCHEMBL2305649 | 0.76 | RAB9A (0.55) | HDAC8HDAC6HDAC2HDAC1TDP1 | |
| SCHEMBL11273200 | 0.75 | SMN1; SMN2 (0.44) | HDAC8HDAC6MEN1KMT2AHSD17B10 | |
| SCHEMBL3070802 | 0.74 | FFAR1 (0.43) | TDP1MEN1KMT2AHSD17B10CYP1A2 | |
| SCHEMBL5178134 | 0.74 | FFAR1 (0.43) | TDP1MEN1KMT2AHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313892-A | VULCANIZATION INHIBITORS | MONSANTO COMPANY (US) | 1982-02-02 | — | — | US | disclosed |
| US-4248805-A | Vulcanizable rubber compositions containing N-(sulfenyl) phthalamides as scorch inhibitors | MONSANTO COMPANY (US) | 1981-02-03 | — | — | US | disclosed |