SCHEMBL5178134

SCHEMBL5178134

O=C(O)NSc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.43
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
SMN1; SMN2 Q16637 5/20 0.39
MAPT P10636 5/20 0.39
HPGD P15428 4/20 0.39
HSD17B10 Q99714 2/20 0.39
MGLL Q99685 1/20 0.39
ALDH1A1 P00352 3/20 0.39
MTNR1A P48039 4/20 0.38
MTNR1B P49286 4/20 0.38
CYP3A4 P08684 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
LMNA P02545 2/20 0.37
RECQL P46063 1/20 0.37
TP53 P04637 2/20 0.37
MEN1 O00255 2/20 0.37
MAPK1 P28482 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3070802 0.85 FFAR1 (0.43) FFAR1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL132621 0.85 SMN1; SMN2 (0.46) FFAR1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL133966 0.81 FFAR1 (0.40) FFAR1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL3071125 0.81 FFAR1 (0.45) FFAR1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL10431593 0.81 MTNR1A (0.48) FFAR1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL158241 0.81 SIRT1 (0.42) FFAR1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL11768134 0.81 ALDH1A1 (0.44) NPC1RAB9ASMN1; SMN2MAPTHPGD
SCHEMBL27502838 0.79 NPC1 (0.53) NPC1RAB9ASMN1; SMN2MAPTHPGD
SCHEMBL9721632 0.79 CYP1A2 (0.47) FFAR1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL11262828 0.79 NPC1 (0.48) NPC1RAB9ASMN1; SMN2MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030050248-A1 Novel amino acid and peptide inhibitors of Staphylococcus virulence PANORAMA RESEARCH, INC. 2003-03-13 US claimed
EP-1261362-A2 NOVEL AMINO ACID AND PEPTIDE INHIBITORS OF STAPHYLOCOCCUS VIRULENCE Intermune, Inc. (US) 2002-12-04 EP claimed
WO-2001058471-A2 NOVEL AMINO ACID AND PEPTIDE INHIBITORS OF STAPHYLOCOCCUS VIRULENCE INTERMUNE, INC. (US) 2001-08-16 WO claimed
JP-60185704-A None JP disclosed
CN-114585370-A Oligonucleotide compositions and methods of use thereof 波涛生命科学有限公司 2022-06-03 CN disclosed
CN-114502177-A Oligonucleotide compositions and methods of use thereof 波涛生命科学有限公司 2022-05-13 CN disclosed
CN-113748116-A Techniques useful for oligonucleotide preparation 波涛生命科学有限公司 2021-12-03 CN disclosed
CN-113383078-A Oligonucleotide compositions and methods thereof 波涛生命科学有限公司 2021-09-10 CN disclosed
CN-112218664-A Oligonucleotide compositions and methods of use thereof 波涛生命科学有限公司 2021-01-12 CN disclosed
CN-112004928-A Oligonucleotide compositions and methods of use thereof 波涛生命科学有限公司 2020-11-27 CN disclosed
WO-2019167814-A1 METHOD FOR PRODUCING MERCAPTOPHENOL COMPOUND AND INTERMEDIATE OF SAID COMPOUND クミアイ化学工業株式会社 2019-09-06 WO disclosed
EP-0814807-A1 TRICYCLIC COMPOUNDS USEFUL FOR INHIBITION OF G-PROTEIN FUNCTION AND FOR TREATMENT OF PROLIFERATIVE DISEASES SCHERING CORPORATION (US) 1998-01-07 EP disclosed
WO-1996030017-A1 TRICYCLIC COMPOUNDS USEFUL FOR INHIBITION OF G-PROTEIN FUNCTION AND FOR TREATMENT OF PROLIFERATIVE DISEASES SCHERING CORPORATION (US) 1996-10-03 WO disclosed
WO-1995006254-A1 SITE-SPECIFIC COVALENT ATTACHMENT OF CONGLUTININ TO SOLID PHASE MATERIALS AND RELATED METHODS APPLIED IMMUNE SCIENCES, INC. (US) 1995-03-02 WO disclosed
US-5360819-A Nonradioactive labels which provide a ketone signal, vapor phase analysis NORTHEASTERN UNIVERSITY (US) 1994-11-01 US disclosed
US-4709016-A Molecular analytical release tags and their use in chemical analysis NORTHEASTERN UNIVERSITY (US) 1987-11-24 US disclosed
US-4650750-A Method of chemical analysis employing molecular release tag compounds GIESE ROGER W (US) 1987-03-17 US disclosed
JP-S60185704-A FUNGICIDE FOR AGRICULTURAL AND HORTICULTURAL PURPOSES ISHIHARA SANGYO KAISHA LTD 1985-09-21 JP disclosed
EP-0085554-A1 Molecular analytical release tags and their use in chemical analysis NORTHEASTERN UNIVERSITY (US) 1983-08-10 EP disclosed
US-4028394-A Antibacterial and fungicidal S-phenylthiocarbamates R. T. VANDERBILT COMPANY, INC. (US) 1977-06-07 US disclosed