Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27502838 | 0.96 | NPC1 (0.53) | NPC1RAB9AHDAC1HDAC2HDAC8 | |
| SCHEMBL28626503 | 0.86 | NPC1 (0.50) | NPC1RAB9AHDAC1HDAC8HDAC6 | |
| SCHEMBL11263588 | 0.86 | HDAC8 (0.47) | NPC1RAB9AHDAC1HDAC2HDAC8 | |
| SCHEMBL11972682 | 0.85 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2TDP1MAPT | |
| SCHEMBL30984376 | 0.83 | ALDH1A1 (0.56) | NPC1RAB9AHDAC1HDAC6SMN1; SMN2 | |
| SCHEMBL14268630 | 0.83 | KMT2A (0.50) | NPC1RAB9AHDAC1HDAC2HDAC8 | |
| SCHEMBL2305649 | 0.80 | RAB9A (0.55) | NPC1RAB9AHDAC1HDAC2HDAC8 | |
| SCHEMBL3070802 | 0.79 | FFAR1 (0.43) | NPC1RAB9AALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL5178134 | 0.79 | FFAR1 (0.43) | NPC1RAB9AALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL132621 | 0.79 | SMN1; SMN2 (0.46) | NPC1RAB9AALOX15HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313892-A | VULCANIZATION INHIBITORS | MONSANTO COMPANY (US) | 1982-02-02 | — | — | US | disclosed |
| US-4248805-A | Vulcanizable rubber compositions containing N-(sulfenyl) phthalamides as scorch inhibitors | MONSANTO COMPANY (US) | 1981-02-03 | — | — | US | disclosed |