Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 7/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 7/20 | 0.42 |
| ▸ | RELA | Q04206 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21358235 | 0.83 | CYP1A2 (0.47) | NFKB1NFKB2RELAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL14741343 | 0.82 | CYP1A2 (0.46) | NFKB1NFKB2RELAMEN1KMT2A | |
| SCHEMBL21359924 | 0.82 | MEN1 (0.41) | NFKB1NFKB2RELAMEN1KMT2A | |
| SCHEMBL4974159 | 0.76 | ACHE (0.38) | KMT2AKDM4EHSD17B10CYP1A2CYP2D6 | |
| SCHEMBL30358013 | 0.76 | HTR1A (0.47) | CYP1A2CYP2C9MAPTALOX15 | |
| SCHEMBL8567081 | 0.75 | SMYD3 (0.56) | MEN1KMT2AKDM4EHSD17B10CYP1A2 | |
| SCHEMBL30357995 | 0.75 | SMYD3 (0.56) | MEN1KMT2AKDM4EHSD17B10CYP1A2 | |
| SCHEMBL7433964 | 0.75 | SMYD3 (0.56) | MEN1KMT2AKDM4EHSD17B10CYP1A2 | |
| SCHEMBL926907 | 0.75 | SMYD3 (0.56) | MEN1KMT2AKDM4EHSD17B10CYP1A2 | |
| SCHEMBL6740937 | 0.74 | ADRA2A (0.38) | NFKB1NFKB2RELAKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328230-A | N-Substituted-quinolin-4-one-2-carboxic acid derivatives | FISONS LIMITED (GB) | 1982-05-04 | — | — | US | disclosed |