Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264495 | 0.79 | ACHE (0.56) | ACHEHDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL11273798 | 0.79 | GAA (0.50) | KMT2AACHEHDAC1HDAC8HDAC3 | |
| SCHEMBL11272205 | 0.79 | NPC1 (0.50) | MEN1KMT2AHDAC1HDAC8HDAC3 | |
| SCHEMBL19474733 | 0.75 | MEP1B (0.66) | — | |
| SCHEMBL28703900 | 0.75 | ACHE (0.68) | MEN1HPGDKMT2AACHENPC1 | |
| SCHEMBL8243910 | 0.75 | L3MBTL1 (0.69) | MEN1HPGDKMT2AHDAC1HDAC8 | |
| Bicarbonate SCHEMBL722688 | 0.75 | ACHE (0.75) | MEN1HPGDKMT2AACHENPC1 | |
| Bicarbonate SCHEMBL2285222 | 0.75 | ACHE (0.75) | MEN1HPGDKMT2AACHENPC1 | |
| Methyl Carbamate SCHEMBL28653549 | 0.74 | ACHE (0.65) | MEN1HPGDKMT2AACHENPC1 | |
| 4-Nitrotoluene SCHEMBL11265976 | 0.73 | ACHE (0.58) | MMP1MEN1KMT2AACHEHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325964-A | SEDATIVES, MUSCLE RELAXANTS, HYPOTENSIVE AGENTS | LABORATOIRE L. LAFON (FR) | 1982-04-20 | — | — | US | claimed |
| US-4325964-A | SEDATIVES, MUSCLE RELAXANTS, HYPOTENSIVE AGENTS | LABORATOIRE L. LAFON (FR) | 1982-04-20 | — | — | US | disclosed |