Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.75 |
| ▸ | CA1 | P00915 | 4/20 | 0.60 |
| ▸ | CA2 | P00918 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 2/20 | 0.56 |
| ▸ | CES1 | P23141 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL722688 | 1.00 | ACHE (0.75) | ACHECA1CA2LMNANPC1 | |
| Acetic Acid SCHEMBL28408918 | 0.93 | ACHE (0.71) | ACHECA1CA2LMNANPC1 | |
| Methyl Alcohol SCHEMBL20136156 | 0.87 | ACHE (0.88) | ACHECA1CA2LMNANPC1 | |
| Benzene SCHEMBL11242974 | 0.87 | ACHE (0.88) | ACHECA1CA2LMNANPC1 | |
| P-Anisic Acid SCHEMBL9101775 | 0.87 | CA1 (0.83) | ACHECA1CA2NPC1RAB9A | |
| SCHEMBL12464 | 0.87 | — | — | |
| SCHEMBL13925529 | 0.87 | — | — | |
| SCHEMBL19182839 | 0.87 | ACHE (1.00) | ACHECA1CA2LMNANPC1 | |
| SCHEMBL28703900 | 0.86 | ACHE (0.68) | ACHECA1CA2LMNANPC1 | |
| Acetamide SCHEMBL28284147 | 0.86 | ACHE (0.68) | ACHECA1CA2LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1801095-B1 | PROCESS FOR PRODUCTION OF HIGH-PURITY DIARYL CARBONATE | ASAHI KASEI CHEMICALS CORP (JP) | 2012-07-18 | — | — | EP | disclosed |
| US-8044167-B2 | aromatic polycarbonates made therefrom; alkyl aryl carbonate obtained through a transesterification reaction between a dialkyl carbonate and an aromatic monohydroxy compound, with reactive distillation using three columns, each operated under specified distillation conditions; discoloration inhibition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-10-25 | — | — | US | disclosed |
| US-8044226-B2 | Process for production of high-purity diaryl carbonate | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-10-25 | — | — | US | disclosed |
| US-8039659-B2 | Processes for preparing diaryl and/or alkylaryl carbonates from dialkyl carbonates | BAYER MATERIALSCIENCE AG (DE) | 2011-10-18 | — | — | US | disclosed |
| US-20110206568-A1 | PROCESS FOR THE PREPARATION OF DIARYL CARBONATES OR ARYLALKYL CARBONATES FROM DIALKYL CARBONATES | BAYER MATERIALSCIENCE AG (DE) | 2011-08-25 | — | — | US | disclosed |
| US-8003817-B2 | Process for the preparation of diaryl carbonates or arylalkyl carbonates from dialkyl carbonates | BAYER MATERIALSCIENCE AG (DE) | 2011-08-23 | — | — | US | disclosed |
| US-7622601-B2 | Process for production of high-purity diaryl carbonate | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2009-11-24 | — | — | US | disclosed |
| US-20090287012-A1 | PROCESS FOR PRODUCTION OF HIGH-PURITY DIARYL CARBONATE | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2009-11-19 | — | — | US | disclosed |
| US-20090287014-A1 | PROCESS FOR PRODUCTION OF HIGH-PURITY DIARYL CARBONATE | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2009-11-19 | — | — | US | disclosed |
| US-20090076293-A1 | PROCESSES FOR PREPARING DIARYL AND/OR ALKYLARYL CARBONATES FROM DIALKYL CARBONATES | BAYER MATERIALSCIENCE AG (DE) | 2009-03-19 | — | — | US | disclosed |
| US-20080293960-A1 | Process For The Preparation Of Diaryl Carbonates Or Arylalkyl Carbonates From Dialkyl Carbonates | BAYER MATERIALSCIENCE AG (DE) | 2008-11-27 | — | — | US | disclosed |
| US-20070270604-A1 | Process for Production of High-Purity Diaryl Carbonate | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2007-11-22 | — | — | US | disclosed |
| US-20070260084-A1 | Industrial Process for Production of High-Purity Diaryl Carbonate | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2007-11-08 | — | — | US | disclosed |
| EP-1803704-A1 | PROCESS FOR PRODUCING HIGH-PURITY DIARYL CARBONATE ON COMMERICAL SCALE | Asahi Kasei Chemicals Corporation (JP) | 2007-07-04 | — | — | EP | disclosed |
| EP-1801095-A1 | PROCESS FOR PRODUCTION OF HIGH-PURITY DIARYL CARBONATE | Asahi Kasei Chemicals Corporation (JP) | 2007-06-27 | — | — | EP | disclosed |
| US-5354923-A | Transesterificatin using titanium dioxide as catalyst | BAYER AKTIENGESELLSCHAFT (DE) | 1994-10-11 | — | — | US | disclosed |
| US-5149856-A | Transesterification; reacting carbonic acid diester containing atleast one aliphatic ester group and phenols to form carbonic acid diester with atleast one aromatic ester group, using polymeric hydroxystannoxanes catalyst | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293960-A1 | Process For The Preparation Of Diaryl Carbonates Or Arylalkyl Carbonates From Dialkyl Carbonates | HDHD5, ALKBH3, AHR | ACHE 4055/4885CA1 594/4885CA2 35/4885 |
| US-20090076293-A1 | PROCESSES FOR PREPARING DIARYL AND/OR ALKYLARYL CARBONATES FROM DIALKYL CARBONATES | DHCR7, ADH1C, AKR1C4 | ACHE 1379/4885CA1 866/4885CA2 565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.