Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | PTPRF | P10586 | 1/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28122216 | 0.98 | MAPT (0.58) | MAPTMEN1KMT2AALDH1A1GLA | |
| Urea SCHEMBL28444611 | 0.95 | MAPT (0.54) | MAPTMEN1KMT2AALDH1A1GLA | |
| SCHEMBL9543117 | 0.87 | MAPT (0.52) | MAPTMEN1KMT2AALDH1A1GLA | |
| SCHEMBL3989574 | 0.84 | ESR1 (0.67) | MAPTMEN1KMT2AALDH1A1GLA | |
| SCHEMBL28935012 | 0.84 | MAPT (0.62) | MAPTMEN1KMT2AALDH1A1GLA | |
| SCHEMBL16306796 | 0.82 | MAPT (0.66) | MAPTMEN1KMT2AALDH1A1GLA | |
| SCHEMBL6259751 | 0.82 | ALDH1A1 (0.59) | MAPTMEN1KMT2AALDH1A1GLA | |
| SCHEMBL5692310 | 0.82 | ALDH1A1 (0.44) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7326754 | 0.81 | ALOX5 (0.48) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1258976 | 0.81 | MAPT (0.59) | MAPTMEN1KMT2AALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118079030-A | Drug-loaded polymer nano micelle and preparation method and application thereof | 郑州大学 | 2024-05-28 | — | — | CN | claimed |
| CN-104163765-A | New method for reactive extraction of 4-nitro-phenylglycine | HUNAN INST SCIENCE & TECH | 2014-11-26 | — | — | CN | claimed |
| CN-118079030-A | Drug-loaded polymer nano micelle and preparation method and application thereof | 郑州大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-106380415-B | A kind of preparation method of D, L- phenylglycine and the like | 宁夏紫光天化蛋氨酸有限责任公司 | 2019-01-22 | — | — | CN | disclosed |
| US-9850287-B2 | Means and methods for breaking noncovalent binding interactions between molecules | HET NEDERLANDS KANKER INSTITUUT (NL) | 2017-12-26 | — | — | US | disclosed |
| EP-1224170-B9 | 6-POSITION SUBSTITUTED INDOLINE, PRODUCTION AND USE THEREOF AS A MEDICAMENT | BOEHRINGER INGELHEIM PHARMA (DE) | 2017-11-22 | — | — | EP | disclosed |
| US-9732109-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2017-08-15 | — | — | US | disclosed |
| US-20170145060-A9 | MEANS AND METHODS FOR BREAKING NONCOVALENT BINDING INTERACTIONS BETWEEN MOLECULES | HET NEDERLANDS KANKER INSTITUUT (NL) | 2017-05-25 | — | — | US | disclosed |
| CN-106380415-A | Preparation method for D, L-phenylglycine and analogue thereof | 宁夏紫光天化蛋氨酸有限责任公司 | 2017-02-08 | — | — | CN | disclosed |
| EP-2247603-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-09-28 | — | — | EP | disclosed |
| US-9452168-B2 | Pyrrole antifungal agents | F2G LTD (GB) | 2016-09-27 | — | — | US | disclosed |
| US-4343802-A | ADRENERGIC BLOCKING, ANTIARRYHYTHMIA, AND CARDIOTONIC AGENTS | MERCK, SHARP & DOHME (I.A.) CORP. (US) | 1982-08-10 | — | — | US | disclosed |
| US-4193995-A | B-ADRENERGIC BLOCKING AGENTS | MERCK SHARP & DOHME (I.A.) CORP. (US) | 1980-03-18 | — | — | US | disclosed |
| US-4116949-A | WATER-SOLUBLE, PHYSIOLOGICALLY ACTIVE, SYNTHETIC COPOLYPEPTIDES | THE REAGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1978-09-26 | — | — | US | disclosed |
| US-4086341-A | NITRO SUBSTITUTED; ANTIBIOTIC | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-25 | — | — | US | disclosed |
| US-4042586-A | ADRENERGIC BLOCKING AGENTS | MERCK SHARP & DOHME (I.A.) CORPORATION (US) | 1977-08-16 | — | — | US | disclosed |
| US-4029806-A | Nitro-β-lactam antibiotics and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-14 | — | — | US | disclosed |
| US-4012518-A | PENICILLIN DERIVATIVES AS GROWTH AND FEED UTILIZATION PROMOTERS IN ANIMALS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-15 | — | — | US | disclosed |
| US-3946009-A | ADRENERGIC BLOCKING AGENTS | MERCK SHARP & DOHME (I.A.) CORPORATION (US) | 1976-03-23 | — | — | US | disclosed |
| US-3930792-A | NITROAMINOBENZENE, QUATERNARY AMINE, N-OXYALKYLATED FATTY ACID AMIDES | CLAIROL INCORPORATED (US) | 1976-01-06 | — | — | US | disclosed |