Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | PTPRF | P10586 | 1/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1024700 | 0.84 | MAPT (0.61) | MAPTMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL4955548 | 0.83 | MAPT (0.70) | MAPTMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL9003269 | 0.83 | MAPT (0.70) | MAPTMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL11022003 | 0.82 | MAPT (0.59) | MAPTMEN1KMT2AALDH1A1GLA | |
| Ammonia Solution, Strong SCHEMBL27496286 | 0.82 | ABCG2 (0.61) | MAPTMEN1KMT2AALDH1A1GLA | |
| SCHEMBL1126414 | 0.82 | MAPT (0.59) | MAPTMEN1KMT2AALDH1A1GLA | |
| SCHEMBL9820311 | 0.81 | ALDH1A1 (0.65) | MAPTMEN1KMT2AALDH1A1GLA | |
| SCHEMBL3989574 | 0.81 | ESR1 (0.67) | MAPTMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL28122216 | 0.81 | MAPT (0.58) | MAPTMEN1KMT2AALDH1A1GLA | |
| SCHEMBL28935012 | 0.81 | MAPT (0.62) | MAPTMEN1KMT2AALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093330-B | Preparation method of p-phenylenediamine | 中化环境科技工程有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-117466749-A | Method for preparing aromatic diamine from aromatic nitro compound | 宁夏信广和新材料科技有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-115093330-A | Preparation method of p-phenylenediamine | 中化环境科技工程有限公司 | 2022-09-23 | — | — | CN | disclosed |
| US-20150004134-A1 | TREATMENT OF CANCER WITH HETEROCYCLIC INHIBITORS OF GLUTAMINASE | CALITHERA BIOSCIENCES, INC. (US) | 2015-01-01 | — | — | US | disclosed |
| US-20140369961-A1 | HETEROCYCLIC INHIBITORS OF GLUTAMINASE | CALITHERA BIOSCIENCES INC. | 2014-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140369961-A1 | HETEROCYCLIC INHIBITORS OF GLUTAMINASE | GLS, GLS2, GLUL | MAPT 3123/4885MEN1 1027/4885KMT2A 850/4885 |
| US-20150004134-A1 | TREATMENT OF CANCER WITH HETEROCYCLIC INHIBITORS OF GLUTAMINASE | GLS, GLS2, GLUL | MAPT 4290/4885MEN1 1270/4885KMT2A 533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.