Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | GLA | P06280 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 11/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MPI | P34949 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509667 | 0.90 | ALDH1A1 (0.64) | ALDH1A1GLASMN1; SMN2MAPTHPGD | |
| SCHEMBL4829828 | 0.87 | ALDH1A1 (0.61) | ALDH1A1GLASMN1; SMN2MAPTHPGD | |
| SCHEMBL9840107 | 0.87 | ALDH1A1 (0.61) | ALDH1A1GLASMN1; SMN2MAPTHPGD | |
| SCHEMBL29170682 | 0.85 | ALDH1A1 (0.66) | ALDH1A1GLASMN1; SMN2MAPTHPGD | |
| SCHEMBL9003269 | 0.83 | MAPT (0.70) | ALDH1A1GLASMN1; SMN2MAPTHPGD | |
| SCHEMBL1126414 | 0.82 | MAPT (0.59) | ALDH1A1GLASMN1; SMN2MAPTHPGD | |
| SCHEMBL7984789 | 0.81 | MAPT (0.64) | ALDH1A1GLASMN1; SMN2MAPTHPGD | |
| SCHEMBL27182713 | 0.81 | POLB (0.66) | ALDH1A1SMN1; SMN2MAPTHPGDPOLB | |
| SCHEMBL28122216 | 0.81 | MAPT (0.58) | ALDH1A1GLASMN1; SMN2MAPTHPGD | |
| SCHEMBL1024700 | 0.80 | MAPT (0.61) | ALDH1A1GLASMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1580186-A1 | Secondary p-phenylendiamines containing a carboxylic acid group, dye composition containing them, processes and uses | L'OREAL (FR) | 2005-09-28 | — | — | EP | disclosed |