Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 3/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11257808 | 0.86 | MAPT (0.44) | POLBALDH1A1PPARGPPARA | |
| SCHEMBL11255842 | 0.82 | ALDH1A1 (0.40) | POLBALDH1A1HSD17B10 | |
| SCHEMBL11265227 | 0.82 | HSD17B10 (0.46) | POLBAKR1C3AKR1C2PTGS1PDE4B | |
| SCHEMBL11259896 | 0.82 | CDK4 (0.39) | HPGDALDH1A1 | |
| SCHEMBL11267339 | 0.81 | POLB (0.43) | POLBPDE4BHPGDALDH1A1CYP1A2 | |
| SCHEMBL9687675 | 0.80 | POLB (0.56) | POLBPDE4BHPGDALDH1A1CYP1A2 | |
| SCHEMBL11259485 | 0.79 | LTB4R (0.44) | POLBALDH1A1 | |
| SCHEMBL11259607 | 0.78 | MAPT (0.44) | POLBALDH1A1PPARGPPARA | |
| SCHEMBL11275814 | 0.76 | ABCB1 (0.43) | POLBAKR1C3AKR1C2PTGS1HPGD | |
| SCHEMBL19577299 | 0.74 | MAPT (0.39) | HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322439-A | ω-[2-(N-Lower alkyl-benzamido)-phenyl]-alkanoic acids, their use, and medicaments containing them | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-03-30 | — | — | US | disclosed |
| WO-1979000586-A1 | W-(2-N-LOWER ALKYL-BENZAMIDO)-PHENYL)-ALKANOIC ACIDS,THEIR USE AND PREPARATION,AND MEDICAMENTS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1979-08-23 | — | — | WO | disclosed |