Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130531 | 0.92 | KMT2A (0.42) | GAAMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL20514279 | 0.82 | ALDH1A1 (0.50) | KMT2AALDH1A1KDM4EHPGDCYP1A2 | |
| SCHEMBL6656374 | 0.82 | ALDH1A1 (0.50) | KMT2AALDH1A1KDM4EHPGDCYP1A2 | |
| SCHEMBL5860496 | 0.82 | CYP2D6 (0.50) | GAAGLAPPARGPPARA | |
| SCHEMBL9127785 | 0.81 | TDP1 (0.45) | GAAMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL5327049 | 0.78 | CASP1 (0.56) | GAAMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL6788195 | 0.78 | POLB (0.48) | GAAMEN1KMT2ANPC1KDM4E | |
| SCHEMBL10650360 | 0.78 | PIN1 (0.42) | MEN1KMT2AALDH1A1NPC1KDM4E | |
| SCHEMBL9127430 | 0.78 | L3MBTL1 (0.49) | GAAMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL11273360 | 0.77 | PIN1 (0.41) | MEN1KMT2ANPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4351842-A | N-Cyclopropylisoindolines | GLAXO LABORATORIES LIMITED (GB) | 1982-09-28 | — | — | US | disclosed |