Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL270111 | 0.79 | GABRA1 (0.52) | SLC6A4SLC6A2SLC6A3SIGMAR1 | |
| SCHEMBL15702021 | 0.78 | P4HB (0.50) | P4HBHTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL13020024 | 0.78 | P4HB (0.50) | P4HBHTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL1724429 | 0.77 | SLC6A2 (0.52) | HTR2AHTR2CHTR2BSLC6A4SLC6A2 | |
| SCHEMBL15701863 | 0.76 | P4HB (0.49) | P4HBHTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL8411705 | 0.76 | P4HB (0.66) | P4HBHTR2AHTR2CHTR2BMAOB | |
| SCHEMBL11135844 | 0.76 | TAAR1 (0.50) | P4HBHTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL16197829 | 0.75 | FDPS (0.39) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL4931748 | 0.75 | FDPS (0.39) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| Bromide SCHEMBL6322805 | 0.74 | TAAR1 (0.48) | P4HBHTR2AHTR2CHTR2BSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333930-A | TREATMENT OF CENTRAL NERVOUS DISORDERS, ANALGESICS, ANTIDEPRESSANTS | LABORATOIRES SARGET (FR) | 1982-06-08 | — | — | US | disclosed |