Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 1/20 | 0.66 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28796414 | 0.82 | P4HB (0.47) | P4HBHTR2AHTR2CHTR2BHSPA5 | |
| SCHEMBL108067 | 0.79 | GABRA1 (0.64) | HSPA5POLBMAPK1TSHRCYP2D6 | |
| SCHEMBL15702021 | 0.78 | P4HB (0.50) | P4HBHTR2AHTR2CHTR2BCYP2D6 | |
| SCHEMBL13020024 | 0.78 | P4HB (0.50) | P4HBHTR2AHTR2CHTR2BCYP2D6 | |
| SCHEMBL536816 | 0.77 | HSPA5 (0.52) | HSPA5POLBMAPK1TSHRCYP2D6 | |
| SCHEMBL27513033 | 0.77 | GABRA1 (0.61) | HSPA5POLBMAPK1TSHRCYP2D6 | |
| SCHEMBL15701863 | 0.76 | P4HB (0.49) | P4HBHTR2AHTR2CHTR2BMAPK1 | |
| SCHEMBL11264459 | 0.76 | P4HB (0.49) | P4HBHTR2AHTR2CHTR2BMAOB | |
| SCHEMBL11135844 | 0.76 | TAAR1 (0.50) | P4HBHTR2AHTR2CHTR2BTSHR | |
| SCHEMBL27323217 | 0.76 | P4HB (0.49) | P4HBHTR2AHTR2CHTR2BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869484-A | TREATING DISEASES DERIVED BY ACETYLCHOLINE DEFICIENCY; ALZHEIMER*S DISEASE | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1999-02-09 | — | — | US | disclosed |