Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 12/20 | 0.42 |
| ▸ | BCHE | P06276 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzophenone SCHEMBL11266176 | 0.90 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1NPC1RAB9ATSHR | |
| Benzophenone SCHEMBL11271133 | 0.90 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1TSHR | |
| Benzophenone SCHEMBL11268574 | 0.86 | TDP1 (0.41) | SMN1; SMN2NPC1RAB9A | |
| Benzophenone SCHEMBL11274446 | 0.86 | TSHR (0.42) | SMN1; SMN2ACHEBCHETSHR | |
| SCHEMBL11193116 | 0.86 | SMN1; SMN2 (0.49) | SMN1; SMN2ACHEBCHEALDH1A1NPC1 | |
| SCHEMBL11264643 | 0.85 | PTGS2 (0.48) | SMN1; SMN2ACHEBCHEALDH1A1KDM4E | |
| Benzophenone SCHEMBL11269386 | 0.83 | TSHR (0.40) | SMN1; SMN2TSHR | |
| Benzophenone SCHEMBL11271776 | 0.83 | TSHR (0.40) | SMN1; SMN2ACHEBCHENPC1RAB9A | |
| Benzophenone SCHEMBL11258074 | 0.83 | ABCB11 (0.49) | SMN1; SMN2ACHEALDH1A1HTTKDM4E | |
| SCHEMBL11154868 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2ACHEBCHEALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |