Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276735 | 0.81 | GPR35 (0.47) | GPR35LMNAALDH1A1POLBMAPT | |
| SCHEMBL11275323 | 0.80 | GPR35 (0.33) | GPR35LMNAALDH1A1POLBMAPT | |
| SCHEMBL21093603 | 0.75 | MAPT (0.51) | GPR35CYP1A2CYP2C9LMNAALDH1A1 | |
| SCHEMBL11278189 | 0.69 | KDM4E (0.50) | GPR35CYP1A2LMNAALDH1A1KDM4E | |
| SCHEMBL4250005 | 0.67 | GPR35 (1.00) | GPR35LMNAALDH1A1KDM4E | |
| SCHEMBL11274923 | 0.67 | GPR35 (0.43) | GPR35POLBMAPTKMT2AHTT | |
| SCHEMBL19744203 | 0.66 | GPR35 (0.65) | GPR35 | |
| SCHEMBL11270041 | 0.66 | ALDH1A1 (0.53) | GPR35ALDH1A1KMT2AKDM4E | |
| SCHEMBL4252552 | 0.65 | ALDH1A1 (0.60) | GPR35ALDH1A1POLBKDM4E | |
| SCHEMBL7889310 | 0.65 | GPR35 (0.47) | GPR35CYP1A2CYP2C9LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316904-A | Indolopyrone tetrazoles and carboxamidotetrazoles having antiallergic activity | WARNER-LAMBERT COMPANY | 1982-02-23 | — | — | US | disclosed |