Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269598 | 0.87 | PKM (0.41) | GPR35CYP3A4CYP2C19PKMPOLB | |
| SCHEMBL11264857 | 0.80 | GPR35 (0.50) | GPR35PKMPOLBMEN1KMT2A | |
| SCHEMBL11284580 | 0.78 | CSNK2A2 (0.39) | CYP3A4CYP2C19POLBMEN1KMT2A | |
| SCHEMBL11285888 | 0.76 | POLB (0.40) | POLBLMNAMAPT | |
| SCHEMBL11273550 | 0.75 | MAPT (0.39) | GPR35POLBMAPT | |
| SCHEMBL11270977 | 0.70 | MAPT (0.40) | CYP3A4CYP2C19POLBMEN1KMT2A | |
| SCHEMBL11556463 | 0.69 | MEN1 (0.49) | GPR35CYP3A4CYP2C19PKMPOLB | |
| SCHEMBL12892208 | 0.68 | ALOX5 (0.51) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL21093603 | 0.66 | MAPT (0.51) | GPR35CYP3A4POLBMEN1KMT2A | |
| SCHEMBL11074319 | 0.65 | CSNK2A2 (0.59) | CYP3A4CYP2C19POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316904-A | Indolopyrone tetrazoles and carboxamidotetrazoles having antiallergic activity | WARNER-LAMBERT COMPANY | 1982-02-23 | — | — | US | disclosed |