Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ACP3 | P15309 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11257484 | 0.90 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL11270945 | 0.90 | LMNA (0.48) | ALDH1A1L3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL11255332 | 0.89 | L3MBTL1 (0.42) | ALDH1A1L3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL11253650 | 0.88 | CACNA1F (0.45) | ALDH1A1L3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL11266663 | 0.88 | MAPT (0.44) | ALDH1A1L3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL11269214 | 0.86 | LMNA (0.43) | ALDH1A1L3MBTL1MEN1KMT2AHPGD | |
| Bicarbonate SCHEMBL11340098 | 0.85 | L3MBTL1 (0.47) | ALDH1A1L3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL11266095 | 0.85 | LMNA (0.40) | ALDH1A1L3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL11254374 | 0.85 | HTT (0.47) | ALDH1A1L3MBTL1SMN1; SMN2HTTMAPT | |
| SCHEMBL11257451 | 0.84 | LMNA (0.40) | ALDH1A1L3MBTL1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360520-A | 1,4-Dihydropyridazine compounds, and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-23 | — | — | US | disclosed |