Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268140 | 0.86 | FFAR1 (0.36) | MAPTKMT2ASIRT1MCL1HTT | |
| SCHEMBL11205751 | 0.79 | DRD4 (0.41) | MAPTKMT2APOLBCYP3A4CYP2C19 | |
| SCHEMBL11271178 | 0.78 | TGM2 (0.43) | MAPTKMT2AHTTTSHRPOLB | |
| SCHEMBL6688633 | 0.75 | MAPT (0.43) | MAPTKMT2ASIRT1HTTTSHR | |
| SCHEMBL11205161 | 0.75 | KMT2A (0.38) | KMT2AHTTPOLBCYP3A4CYP2C19 | |
| SCHEMBL11202360 | 0.74 | LMNA (0.36) | MAPTKMT2AHTTTSHRPOLB | |
| SCHEMBL2945879 | 0.72 | MAPT (0.41) | MAPTKMT2ASIRT1HTTTSHR | |
| SCHEMBL11208369 | 0.70 | MAOA (0.41) | MAPTMCL1TSHRHSD17B10L3MBTL1 | |
| SCHEMBL2951109 | 0.69 | MAOA (0.40) | MAPTTSHRCYP3A4CYP2C19HSD17B10 | |
| SCHEMBL10615654 | 0.68 | MAPT (0.50) | MAPTKMT2AMCL1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342705-A | CONTAINING CARBONYL OR CYANO FUNCTIONAL GROUPS, USEFUL AS VULCANIZATION INHIBITORS | MONSANTO COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| US-4271050-A | Vulcanizable rubber compositions inhibited from premature vulcanization by methylene thioethers | MONSANTO COMPANY (US) | 1981-06-02 | — | — | US | disclosed |