Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265080 | 0.90 | MAPT (0.48) | MAPTSMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL11537463 | 0.83 | MAPT (0.43) | MAPTSMN1; SMN2MAOAMAOBL3MBTL1 | |
| SCHEMBL11539903 | 0.76 | MAPT (0.45) | MAPTMAOAMAOBPTGIRL3MBTL1 | |
| SCHEMBL18235712 | 0.76 | MEN1 (0.47) | L3MBTL1NPC1RAB9APOLBMEN1 | |
| SCHEMBL11539975 | 0.73 | KMT2A (0.41) | MAPTMAPK1SMN1; SMN2L3MBTL1HTT | |
| SCHEMBL9742546 | 0.73 | CYP3A4 (0.47) | MAPTSMN1; SMN2MAOANPC1RAB9A | |
| SCHEMBL3251246 | 0.72 | ALDH1A1 (0.44) | MAPK1SMN1; SMN2L3MBTL1POLBMEN1 | |
| Hydrochloric Acid SCHEMBL8865281 | 0.71 | CYP3A4 (0.46) | MAPTSMN1; SMN2MAOAMAOBNPC1 | |
| SCHEMBL12437151 | 0.71 | ALDH1A1 (0.49) | MAPTSMN1; SMN2NPC1HTTMEN1 | |
| SCHEMBL5320705 | 0.71 | L3MBTL1 (0.46) | MAPTMAPK1SMN1; SMN2L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156011-A | TREATMENT OF CARDIOVASCULAR DISORDERS | SOCIETE ANONYME DITE: LABORATOIRE L. LAFON (FR) | 1979-05-22 | — | — | US | disclosed |