SCHEMBL1126514

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1127347	0.87	CNR1 (0.50)	ALDH1A1CNR1HPGDCNR2
	SCHEMBL1126651	0.86	CNR1 (0.45)	ALDH1A1CNR1P2RX7MCL1MAPT
	SCHEMBL1988373	0.81	CNR1 (0.44)	ALDH1A1L3MBTL1CNR1P2RX7KDM4E
	SCHEMBL1126536	0.74	CNR1 (0.46)	ALDH1A1CNR1TSHRMAPTKDM4E
	SCHEMBL1989510	0.74	CNR1 (0.41)	ALDH1A1L3MBTL1CNR1P2RX7TSHR
	SCHEMBL12584500	0.73	CCNC (0.54)	ALDH1A1MAPK1MAPTKDM4ECNR2
	SCHEMBL1127225	0.73	CCNC (0.41)	ALDH1A1CNR1MAPK1MAPTKDM4E
	SCHEMBL15162603	0.72	GABRA2 (0.45)	L3MBTL1CNR1P2RX7MAPT
	SCHEMBL1126490	0.69	CNR1 (0.42)	ALDH1A1L3MBTL1CNR1P2RX7KDM4E
	SCHEMBL1127836	0.69	P2RX7 (0.41)	ALDH1A1CNR1P2RX7MAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.