SCHEMBL11265304

SCHEMBL11265304

O=C1NC(c2ccccc2)C(=O)O1.[KH]

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 2/20 0.41
GAA P10253 2/20 0.41
KDM4E B2RXH2 1/20 0.41
HPGD P15428 1/20 0.41
GFER P55789 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CA2 P00918 1/20 0.40
LMNA P02545 2/20 0.40
MEN1 O00255 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
TNKS2 Q9H2K2 1/20 0.39
USP2 O75604 1/20 0.37
MAPK10 P53779 1/20 0.37
TSHR P16473 1/20 0.35
PRCP P42785 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4195064 0.98 MAPT (0.42) MAPTKMT2AALDH1A1GAAKDM4E
SCHEMBL4195063 0.98 MAPT (0.42) MAPTKMT2AALDH1A1GAAKDM4E
SCHEMBL164001 0.78 TDP1 (0.50) KMT2AGAAPRCP
SCHEMBL31357816 0.76 KMT2A (0.65) MAPTKMT2AALDH1A1GAAKDM4E
SCHEMBL29965150 0.76 MAPT (0.65) MAPTKMT2AALDH1A1GAAKDM4E
SCHEMBL7218139 0.71 IDO1 (0.38)
SCHEMBL31357782 0.70 LMNA (0.42) MAPTKMT2AALDH1A1KDM4EHSD17B10
SCHEMBL20429730 0.69 SMN1; SMN2 (0.46) MAPTALDH1A1GAACA2LMNA
SCHEMBL1894049 0.69 MAPT (0.48) MAPTKMT2AALDH1A1GAAKDM4E
SCHEMBL1895535 0.69 MAPT (0.48) MAPTKMT2AALDH1A1GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4314023-A AZO-METHINE DYES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1982-02-02 US disclosed