Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3015461 | 0.87 | TAAR1 (0.50) | AOC3TAAR1HTR6CETPITGA2B | |
| SCHEMBL11071906 | 0.84 | AOC3 (0.49) | AOC3TAAR1HTR6ARTP53 | |
| SCHEMBL11063733 | 0.82 | AOC3 (0.47) | AOC3TAAR1HTR6CETPITGA2B | |
| SCHEMBL11265409 | 0.82 | HTR6 (0.52) | AOC3TAAR1HTR6 | |
| SCHEMBL11070162 | 0.81 | SCN4A (0.52) | AOC3TAAR1HTR6CETPHSD17B10 | |
| SCHEMBL11064971 | 0.80 | AOC3 (0.53) | AOC3TAAR1HTR6ITGA2BHSD17B10 | |
| SCHEMBL11071226 | 0.79 | CETP (0.51) | AOC3HTR6CETPSMN1; SMN2RAB9A | |
| SCHEMBL11064399 | 0.79 | AOC3 (0.51) | AOC3HTR6CETPARSMN1; SMN2 | |
| SCHEMBL11064121 | 0.79 | AOC3 (0.51) | AOC3HTR6CETPARHTR3A | |
| SCHEMBL11065972 | 0.76 | AOC3 (0.48) | AOC3HTR6RAB9AHTR3AHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4312869-A | Monosubstituted piperazines | SCIENCE UNION ET CIE (FR) | 1982-01-26 | — | — | US | claimed |
| US-4312869-A | Monosubstituted piperazines | SCIENCE UNION ET CIE (FR) | 1982-01-26 | — | — | US | disclosed |
| US-4312869-A | Monosubstituted piperazines | SCIENCE UNION ET CIE (FR) | 1982-01-26 | — | — | US | disclosed |