Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.60 |
| ▸ | BCHE | P06276 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375848 | 0.89 | BCHE (0.65) | ACHEBCHECYP3A4LMNAFAAH | |
| SCHEMBL29722653 | 0.84 | ACHE (0.61) | ACHEBCHELMNAMEN1KMT2A | |
| SCHEMBL2529775 | 0.84 | BCHE (0.59) | ACHEBCHECYP3A4LMNAFAAH | |
| SCHEMBL28920273 | 0.84 | MEN1 (0.66) | ACHEBCHECYP3A4LMNAFAAH | |
| SCHEMBL2331290 | 0.84 | ACHE (0.61) | ACHEBCHELMNAMEN1KMT2A | |
| SCHEMBL9481027 | 0.83 | MTNR1A (0.56) | ACHEBCHECYP3A4LMNAMEN1 | |
| SCHEMBL9407428 | 0.83 | BCHE (0.55) | ACHEBCHECYP3A4LMNAFAAH | |
| SCHEMBL4410973 | 0.82 | LMNA (0.56) | ACHEBCHECYP3A4LMNAMEN1 | |
| SCHEMBL17028900 | 0.82 | LMNA (0.76) | ACHECYP3A4LMNAMEN1KMT2A | |
| SCHEMBL249305 | 0.82 | LMNA (0.76) | ACHECYP3A4LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210363124-A1 | HETEROCYCLYL POLYMETHINE IR CHROMOPHORES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-11-25 | — | — | US | disclosed |
| WO-2020118116-A1 | HETEROCYCLYL POLYMETHINE IR CHROMOPHORES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-06-11 | — | — | WO | disclosed |
| US-20200140404-A1 | HETEROCYCLYL POLYMETHINE IR CHROMOPHORES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-05-07 | — | — | US | disclosed |
| US-4351768-A | CARBONLESS, DUPLICATION, INDOLE DYES | STERLING DRUG INC. (US) | 1982-09-28 | — | — | US | disclosed |
| US-4322352-A | Indolyl phthalide compounds | STERLING DRUG INC. (US) | 1982-03-30 | — | — | US | disclosed |
| US-4307018-A | CHROMOGENS FOR COPYING SYSTEMS | STERLING DRUG INC. (US) | 1981-12-22 | — | — | US | disclosed |
| US-4251446-A | COLOR PRECURSORS | STERLING DRUG INC. (US) | 1981-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200140404-A1 | HETEROCYCLYL POLYMETHINE IR CHROMOPHORES | SMARCE1, SMARCD1, WDR82 | ACHE 4068/4885BCHE 3045/4885CYP3A4 2339/4885 |
| US-20210363124-A1 | HETEROCYCLYL POLYMETHINE IR CHROMOPHORES | SMARCE1, CRY2, WDR82 | ACHE 4466/4885BCHE 3465/4885CYP3A4 2362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.