Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.38 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSH | P09668 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4928099 | 0.86 | MAPT (0.39) | MAPTMEN1KMT2APLIN1LMNA | |
| SCHEMBL3224035 | 0.83 | MEN1 (0.55) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL8577901 | 0.78 | TP53 (0.58) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL11775139 | 0.78 | MAOB (0.39) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL11565347 | 0.77 | TP53 (0.47) | MAPTTP53KDM4E | |
| SCHEMBL4925194 | 0.76 | TDP1 (0.40) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL11819791 | 0.75 | MAPT (0.39) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL435678 | 0.75 | KDM4E (0.46) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL11781601 | 0.75 | MAPT (0.52) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL10772305 | 0.75 | KDM4E (0.45) | MAPTMEN1KMT2ATP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320133-A | Penicillins and their antibacterial use | SANDOZ LTD. (CH) | 1982-03-16 | — | — | US | disclosed |