Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16287426 | 0.84 | TP53 (0.56) | TP53KDM4EHTTCYP1A2CYP3A4 | |
| SCHEMBL11265544 | 0.77 | MAPT (0.39) | TP53MAPTKDM4E | |
| SCHEMBL7607193 | 0.77 | NFKB1 (0.53) | TP53MAPTKDM4E | |
| SCHEMBL5179024 | 0.76 | TBXAS1 (0.40) | MAPTHDAC8KDM4ECYP3A4CYP2C9 | |
| SCHEMBL7311482 | 0.75 | TRPA1 (0.50) | TP53MAPTHDAC8 | |
| SCHEMBL433478 | 0.75 | TP53 (0.47) | TP53MAPTKDM4EHTTCYP1A2 | |
| SCHEMBL7446722 | 0.75 | ALDH1A1 (0.50) | TP53MAPTKDM4EHTTCYP1A2 | |
| SCHEMBL8515208 | 0.72 | TP53 (0.44) | TP53MAPTKDM4EHTTCYP1A2 | |
| SCHEMBL7189395 | 0.72 | KDM4E (0.71) | TP53MAPTHDAC8KDM4EHTT | |
| SCHEMBL11795578 | 0.72 | CES2 (0.47) | TP53MAPTHDAC8CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003115-A1 | Penicillins, per se and for use as antibacterially active antibiotics and their production | SANDOZ AG (CH) | 1979-07-25 | — | — | EP | disclosed |