Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3224035 | 0.88 | MEN1 (0.55) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL11815879 | 0.87 | GRIK1 (0.42) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL1673522 | 0.87 | KMT2A (0.55) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3218589 | 0.87 | MEN1 (0.55) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL1332953 | 0.86 | TAS1R3 (0.42) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8577901 | 0.86 | TP53 (0.58) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL10772305 | 0.85 | KDM4E (0.45) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6233438 | 0.85 | KMT2A (0.45) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL11330329 | 0.83 | KDM4E (0.43) | KDM4ELMNANR1H4TP53 | |
| SCHEMBL1856660 | 0.83 | PTGS2 (0.43) | KDM4EALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595952-B1 | AGONISTS OF GPR40 | CONNEXIOS LIFE SCIENCES PVT LTD (IN) | 2020-11-18 | — | — | EP | disclosed |
| US-9278915-B2 | Agonists of GPR40 | CONNEXIOS LIFE SCIENCES PVT LTD (IN) | 2016-03-08 | — | — | US | disclosed |
| US-20130237571-A1 | AGONISTS OF GPR40 | Conexios Life Sciences PVT. LTD. (IN) | 2013-09-12 | — | — | US | disclosed |
| EP-2595952-A1 | AGONISTS OF GPR40 | Connexios Life Sciences Pvt. Ltd. (IN) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012011125-A1 | AGONISTS OF GPR40 | CONNEXIOS LIFE SCIENCES PVT. LTD. (IN) | 2012-01-26 | — | — | WO | disclosed |
| EP-1861465-B1 | CHROMOPHORE COATED METAL OXIDE PARTICLES | DSM IP ASSETS BV (NL) | 2010-10-13 | — | — | EP | disclosed |
| US-20090291107-A1 | Chromophore Coated Metal Oxide Particles | DSM IP ASSETS B.V. (NL) | 2009-11-26 | — | — | US | disclosed |
| EP-1861465-A2 | CHROMOPHORE COATED METAL OXIDE PARTICLES | DSMIP Assets B.V. (NL) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006099952-A2 | CHROMOPHORE COATED METAL OXIDE PARTICLES | DSM IP ASSETS B.V. (NL) | 2006-09-28 | — | — | WO | disclosed |
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |
| US-3943094-A | Polymers and copolymers based on alkenoyl-oxybenzylidene-malonic esters as UV-absorbers and polymers stabilized therewith | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291107-A1 | Chromophore Coated Metal Oxide Particles | PPOX, MITF, MC1R | KDM4E 2829/4885ALDH1A1 1116/4885MEN1 538/4885 |
| US-20130237571-A1 | AGONISTS OF GPR40 | GPR65, GPR55, GPR68 | KDM4E 3722/4885ALDH1A1 2410/4885MEN1 2828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.