Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8577901 | 0.92 | TP53 (0.58) | MEN1KMT2AHTTTP53NR1H4 | |
| SCHEMBL435678 | 0.88 | KDM4E (0.46) | MEN1KMT2ATP53NR1H4MAPT | |
| SCHEMBL10772305 | 0.88 | KDM4E (0.45) | MEN1KMT2AHTTTP53NR1H4 | |
| SCHEMBL3218589 | 0.87 | MEN1 (0.55) | MEN1KMT2AHTTTP53MAPT | |
| SCHEMBL1673522 | 0.87 | KMT2A (0.55) | MEN1KMT2AHTTTP53MAPT | |
| SCHEMBL11815879 | 0.87 | GRIK1 (0.42) | MEN1KMT2AHTTTP53MAPT | |
| SCHEMBL11812910 | 0.86 | MEN1 (0.44) | MEN1KMT2AHTTTP53NR1H4 | |
| SCHEMBL1332953 | 0.86 | TAS1R3 (0.42) | MEN1KMT2ANR1H4MAPTAKR1C3 | |
| SCHEMBL11823604 | 0.85 | PTGS2 (0.43) | MEN1KMT2ATP53MAPTAKR1C3 | |
| SCHEMBL6233438 | 0.85 | KMT2A (0.45) | MEN1KMT2AMAPTLMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566109-A | Method for synthesizing carbenicillin sodium pharmaceutical intermediate diethyl(phenylmethylene)malonate | CHENGDU QIANYE LONGHUA PETROLEUM ENG TECH CONSULTING CO LTD | 2016-05-11 | — | — | CN | claimed |
| CN-100509783-C | Pheny(alkyl)carboxylic acid derivatives and dionic phenylalkylheterocyclic derivatives and their use as medicines with serum glucose and/or serum lipid lowering activity | SIGMA TAU IND FARMACEUTI (IT) | 2009-07-08 | — | — | CN | claimed |
| CN-101203278-A | Ultraviolet protection | MERCK PATENT GMBH (DE) | 2008-06-18 | — | — | CN | claimed |
| CN-1617854-A | Pheny(alkyl)carboxylic acid derivatives and dionic phenylalkylheterocyclic derivatives and their use as medicines with serum glucose and/or serum lipid lowering activity | SIGMA TAU IND FARMACEUTI (IT) | 2005-05-18 | — | — | CN | claimed |
| US-3951990-A | CORONARY AGENTS, HYPOTENSIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | claimed |
| CN-115397520-A | Oil-in-water type emulsion cosmetic | 花王株式会社 | 2022-11-25 | — | — | CN | disclosed |
| CN-104640886-B | The manufacture method of manufacture method for the ingredient of solid catalyst of olefin polymerization, the catalyst for olefin polymerization and olefin polymerization | 东邦钛株式会社 | 2018-04-27 | — | — | CN | disclosed |
| CN-105566109-A | Method for synthesizing carbenicillin sodium pharmaceutical intermediate diethyl(phenylmethylene)malonate | CHENGDU QIANYE LONGHUA PETROLEUM ENG TECH CONSULTING CO LTD | 2016-05-11 | — | — | CN | disclosed |
| CN-103764689-B | The manufacture method of solid catalyst component for olefin polymerization, polymerization of olefines catalyzer and olefin polymer | TOHO TITANIUM CO.,LTD. (JP) | 2016-03-30 | — | — | CN | disclosed |
| CN-105008407-A | Process for producing propylene block copolymer | TOHO TITANIUM CO LTD | 2015-10-28 | — | — | CN | disclosed |
| CN-104822712-A | Solid catalyst component for polymerizing olefin, catalyst for polymerizing olefin, and method for producing polymerized olefin | TOHO TITANIUM CO LTD | 2015-08-05 | — | — | CN | disclosed |
| CN-104744252-A | Method for catalyzing condensation reaction between aromatic aldehyde and malonic diester with bionic water-containing heterogeneous catalytic system | UNIV TIANJIN TECHNOLOGY | 2015-07-01 | — | — | CN | disclosed |
| US-4261988-A | ANTICHOLESTEROL AGENTS USED IN ANIMAL HUSBANDRY | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-14 | — | — | US | disclosed |
| US-4001259-A | 3,6-DIAMINO-3,4-DIHYDRO-2-PYRIDONES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-04 | — | — | US | disclosed |
| US-3987176-A | COMPOSITION AND USE OF 3,4-DIHYDROPYRIDONES AS VASODILATORS AND ANTIHYPERTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-19 | — | — | US | disclosed |
| US-3981882-A | HYPOTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-09-21 | — | — | US | disclosed |
| US-3951990-A | CORONARY AGENTS, HYPOTENSIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3951991-A | CORONARY AGENTS, HYPOTENSIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3951992-A | CORONARY, HYPOTENSIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3935222-A | CNS DEPRESSANT, ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1976-01-27 | — | — | US | disclosed |