Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3224035 | 0.92 | MEN1 (0.55) | TP53MAPTMEN1KMT2ANR1H4 | |
| SCHEMBL435678 | 0.86 | KDM4E (0.46) | TP53MAPTMEN1KMT2ANR1H4 | |
| SCHEMBL1673522 | 0.85 | KMT2A (0.55) | TP53MAPTMEN1KMT2AHTT | |
| SCHEMBL11815879 | 0.85 | GRIK1 (0.42) | TP53MAPTMEN1KMT2AHTT | |
| SCHEMBL3218589 | 0.85 | MEN1 (0.55) | TP53MAPTMEN1KMT2AHTT | |
| SCHEMBL1332953 | 0.84 | TAS1R3 (0.42) | MAPTMEN1KMT2ANR1H4LMNA | |
| SCHEMBL6233438 | 0.83 | KMT2A (0.45) | MAPTMEN1KMT2ARAB9ALMNA | |
| SCHEMBL5045097 | 0.81 | KDM4E (0.47) | TP53MAPTMEN1KMT2APOLB | |
| SCHEMBL1856660 | 0.81 | PTGS2 (0.43) | MAPTMEN1KMT2APOLBNPC1 | |
| SCHEMBL11330329 | 0.81 | KDM4E (0.43) | TP53NR1H4LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705545-A | HINDERED AMINE LIGHT STABILIZER COMPOUND FOR THERMOPLASTIC POLYMERS | CLARIANT FINANCE (BVI) LIMITED (VG) | 1998-01-06 | — | — | US | disclosed |
| US-4228067-A | UV Light stabilized polycarbonate composition | BAYER AKTIENGESELLSCHAFT (DE) | 1980-10-14 | — | — | US | disclosed |