Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HSF1 | Q00613 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 2/20 | 0.34 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.34 |
| ▸ | PDE6C | P51160 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268437 | 0.82 | MMP1 (0.41) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL11259620 | 0.79 | HSD17B10 (0.51) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL11395791 | 0.75 | ALDH1A1 (0.38) | ALDH1A1KDM4EGAAHPGDSMN1; SMN2 | |
| SCHEMBL8726366 | 0.75 | PLA2G10 (0.56) | MEN1ALDH1A1KMT2AGAAMMP1 | |
| SCHEMBL11262980 | 0.74 | ALDH1A1 (0.43) | MEN1ALDH1A1KMT2AGAASMN1; SMN2 | |
| SCHEMBL11267916 | 0.73 | CAPN1 (0.48) | ALDH1A1MAPTGAAHPGDMMP1 | |
| SCHEMBL11256499 | 0.73 | NPSR1 (0.49) | ALDH1A1GAAMMP1MMP3MMP9 | |
| SCHEMBL11263507 | 0.73 | LMNA (0.47) | MEN1KMT2AGAAMMP1MMP3 | |
| SCHEMBL11264004 | 0.72 | MMP1 (0.40) | MEN1ALDH1A1MAPTKMT2AGAA | |
| SCHEMBL4646184 | 0.72 | MMP1 (0.46) | KMT2AGAASMN1; SMN2MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005647-B1 | HYDANTOIN COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | Lilly Industries Limited (GB) | 1982-06-09 | — | — | EP | disclosed |
| US-4293563-A | ANTIASTHMATICS | LILLY INDUSTRIES LIMITED (GB) | 1981-10-06 | — | — | US | disclosed |
| US-4241073-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1980-12-23 | — | — | US | disclosed |
| EP-0005647-A1 | Hydantoin compounds, their preparation and pharmaceutical formulations containing them | Lilly Industries Limited (GB) | 1979-11-28 | — | — | EP | disclosed |