Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265705 | 0.82 | MEN1 (0.51) | MMP1MMP3MMP9ALDH1A1HPGD | |
| SCHEMBL11265232 | 0.79 | PLA2G10 (0.48) | MMP1MMP3MMP9ALDH1A1NPSR1 | |
| SCHEMBL8726366 | 0.79 | PLA2G10 (0.56) | MMP1MMP3MMP9ALDH1A1NPSR1 | |
| SCHEMBL11259620 | 0.77 | HSD17B10 (0.51) | MMP1MMP3MMP9ALDH1A1HPGD | |
| SCHEMBL11271882 | 0.74 | PLA2G10 (0.53) | MMP1MMP3MMP9ALDH1A1NPSR1 | |
| SCHEMBL11265378 | 0.72 | SMN1; SMN2 (0.43) | MMP1MMP3MMP9SMN1; SMN2MAPT | |
| SCHEMBL11259867 | 0.71 | ALDH1A1 (0.45) | MMP1MMP3MMP9ALDH1A1KDM4E | |
| SCHEMBL8726569 | 0.71 | HDAC8 (0.46) | SMN1; SMN2MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL4646184 | 0.70 | MMP1 (0.46) | MMP1MMP3MMP9SMN1; SMN2KMT2A | |
| SCHEMBL1361115 | 0.70 | MMP1 (0.46) | MMP1MMP3MMP9SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005647-B1 | HYDANTOIN COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | Lilly Industries Limited (GB) | 1982-06-09 | — | — | EP | disclosed |
| US-4293563-A | ANTIASTHMATICS | LILLY INDUSTRIES LIMITED (GB) | 1981-10-06 | — | — | US | disclosed |
| US-4241073-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1980-12-23 | — | — | US | disclosed |
| EP-0005647-A1 | Hydantoin compounds, their preparation and pharmaceutical formulations containing them | Lilly Industries Limited (GB) | 1979-11-28 | — | — | EP | disclosed |