Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11091143 | 0.85 | MAOB (0.47) | SMN1; SMN2MAOBALDH1A1AKR1B1MEN1 | |
| SCHEMBL11278936 | 0.84 | GPR35 (0.48) | MAPTLMNASMN1; SMN2MAOBALDH1A1 | |
| SCHEMBL11266671 | 0.82 | SRD5A2 (0.51) | LMNASMN1; SMN2ALDH1A1GAATDP1 | |
| SCHEMBL15143796 | 0.79 | MAOB (0.49) | MAPTLMNAMAOBALDH1A1GAA | |
| SCHEMBL11261990 | 0.79 | MAOB (0.44) | MAPTLMNAMAOBALDH1A1AKR1B1 | |
| SCHEMBL28346379 | 0.76 | AKR1B1 (0.45) | MAPTLMNASMN1; SMN2MAOBALDH1A1 | |
| SCHEMBL19755580 | 0.76 | GAA (0.47) | MAPTLMNASMN1; SMN2MAOBALDH1A1 | |
| SCHEMBL571045 | 0.73 | CA12 (0.63) | MAPTLMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL17862227 | 0.71 | GAA (0.50) | MAPTLMNAMAOBALDH1A1GAA | |
| SCHEMBL9645683 | 0.70 | HSD17B10 (0.49) | MAPTLMNASMN1; SMN2MAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364956-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1982-12-21 | — | — | US | disclosed |