Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645447 | 0.82 | ALDH1A1 (0.56) | HSD17B10ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2896486 | 0.81 | ALDH1A1 (0.62) | HSD17B10ALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL9645415 | 0.81 | HSD17B10 (0.48) | HSD17B10ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7437656 | 0.80 | SRD5A2 (0.47) | HSD17B10ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10597819 | 0.79 | ALDH1A1 (0.58) | HSD17B10ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL559271 | 0.79 | ALDH1A1 (0.58) | HSD17B10ALDH1A1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL164673 | 0.78 | TSHR (0.52) | HSD17B10ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9645771 | 0.78 | ALDH1A1 (0.51) | HSD17B10ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL571045 | 0.76 | CA12 (0.63) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL11336074 | 0.76 | CFTR (0.70) | HSD17B10ALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346713-B1 | BENZAMIDINES USEFUL AS ULTRAVIOLET LIGHT ABSORBERS | L. GIVAUDAN & CIE Société Anonyme (CH) | 1992-09-16 | — | — | EP | disclosed |