Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9296440 | 0.91 | SOAT1 (0.39) | SOAT1LTA4HTSHRLMNAALDH1A1 | |
| SCHEMBL3481385 | 0.89 | LTA4H (0.39) | SOAT1LTA4HTSHRLMNACYP3A4 | |
| SCHEMBL706314 | 0.89 | LTA4H (0.43) | SOAT1LTA4HTSHRALDH1A1CYP3A4 | |
| SCHEMBL707442 | 0.89 | LTA4H (0.43) | SOAT1LTA4HTSHRALDH1A1CYP3A4 | |
| SCHEMBL4589385 | 0.89 | SOAT1 (0.37) | SOAT1LTA4HTSHRLMNAALDH1A1 | |
| SCHEMBL704016 | 0.87 | LTA4H (0.44) | SOAT1LTA4HTSHRALDH1A1CYP3A4 | |
| SCHEMBL4590392 | 0.87 | LTA4H (0.35) | SOAT1LTA4HTSHRLMNAALDH1A1 | |
| SCHEMBL9295312 | 0.86 | TSHR (0.39) | SOAT1LTA4HTSHRLMNAALDH1A1 | |
| SCHEMBL702747 | 0.86 | LTA4H (0.43) | SOAT1LTA4HTSHRALDH1A1CYP3A4 | |
| SCHEMBL9504616 | 0.85 | LTA4H (0.36) | SOAT1LTA4HTSHRCYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012622-B1 | 1-TOSLOXY-2,2-ETHYLENEDIOXY-6,10-DIMETHYL UNDECANES AND UNDECENES, PROCESS FOR THE PREPARATION OF 2S*,3R*-3-BENZYLOXY-6,6-ETHYLENE DIOXY-2-METHYL-2-(5'-HYDROXY-4'-METHYLPENTYL)-OXEPANE, AND USE OF THE LATTER FOR THE PREPARATION OF OXEPAN-3-OL DERIVATIVES | ORTHO PHARMACEUTICAL CORPORATION (US) | 1982-12-15 | — | — | EP | disclosed |