Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9296440 | 0.98 | SOAT1 (0.39) | SOAT1LTA4HTSHRTP53CYP3A4 | |
| SCHEMBL4590392 | 0.95 | LTA4H (0.35) | SOAT1LTA4HTSHRTP53CYP3A4 | |
| SCHEMBL11265902 | 0.89 | SOAT1 (0.42) | SOAT1LTA4HTSHRTP53CYP3A4 | |
| SCHEMBL707442 | 0.85 | LTA4H (0.43) | SOAT1LTA4HTSHRCYP3A4MAPK1 | |
| SCHEMBL706314 | 0.85 | LTA4H (0.43) | SOAT1LTA4HTSHRCYP3A4MAPK1 | |
| SCHEMBL3481385 | 0.85 | LTA4H (0.39) | SOAT1LTA4HTSHRTP53CYP3A4 | |
| SCHEMBL704016 | 0.83 | LTA4H (0.44) | SOAT1LTA4HTSHRCYP3A4MAPK1 | |
| SCHEMBL9295312 | 0.82 | TSHR (0.39) | SOAT1LTA4HTSHRTP53CYP3A4 | |
| SCHEMBL702747 | 0.82 | LTA4H (0.43) | SOAT1LTA4HTSHRCYP3A4MAPK1 | |
| SCHEMBL9504616 | 0.81 | LTA4H (0.36) | SOAT1LTA4HTSHRTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008080988-A2 | CYCLOPENTANONE DERIVATIVES, METHOD OF SYNTHESIS AND USES THEREOF | NEUROPHARMA, S.A. (ES) | 2008-07-10 | — | — | WO | disclosed |