Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | REV1 | Q9UBZ9 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1993070 | 0.85 | MAPT (0.39) | DRD2DRD4DRD3NPC1RAB9A | |
| SCHEMBL1992803 | 0.76 | REV1 (0.44) | DRD2DRD4DRD3NPC1RAB9A | |
| SCHEMBL1991665 | 0.75 | HCRTR1 (0.44) | DRD2DRD4DRD3NPC1RAB9A | |
| SCHEMBL1996541 | 0.73 | REV1 (0.40) | DRD2DRD4DRD3SMN1; SMN2REV1 | |
| SCHEMBL1997118 | 0.73 | ALDH1A1 (0.46) | DRD2DRD4DRD3NPC1RAB9A | |
| SCHEMBL1646298 | 0.71 | THRB (0.51) | DRD2DRD4DRD3SMN1; SMN2REV1 | |
| SCHEMBL1646885 | 0.71 | DRD2 (0.43) | DRD2DRD4DRD3SMN1; SMN2REV1 | |
| SCHEMBL1995053 | 0.70 | MAPT (0.40) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL1991453 | 0.70 | REV1 (0.42) | DRD2DRD4DRD3NPC1RAB9A | |
| SCHEMBL1645652 | 0.70 | REV1 (0.43) | DRD2DRD4DRD3SMN1; SMN2REV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |