Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4130439 | 0.85 | LMNA (0.60) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL21841433 | 0.85 | RAB9A (0.50) | KMT2ATDP1LMNAL3MBTL1RAB9A | |
| SCHEMBL2937091 | 0.82 | TDP1 (0.60) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL2933476 | 0.81 | KMT2A (0.58) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL23309651 | 0.80 | RAB9A (0.46) | KMT2ATDP1LMNAL3MBTL1RAB9A | |
| SCHEMBL5085718 | 0.80 | KMT2A (0.92) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL2357688 | 0.79 | KMT2A (0.76) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL13140970 | 0.78 | KMT2A (0.55) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL2134732 | 0.78 | ALDH1A1 (0.57) | KMT2AL3MBTL1RAB9AMAPTALDH1A1 | |
| SCHEMBL10691581 | 0.78 | ALDH1A1 (0.51) | KMT2ATDP1L3MBTL1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348396-A | Substituted 11-oxo-11H-pyrido[2,1-b]quinazolines and method of inhibiting allergic reactions with them | HOFFMANN-LA ROCHE INC. (US) | 1982-09-07 | — | — | US | disclosed |