Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.46 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.43 |
| ▸ | ATP4A | P20648 | 1/20 | 0.37 |
| ▸ | ATP4B | P51164 | 1/20 | 0.37 |
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261528 | 0.91 | HMOX1 (0.47) | NOS1HMOX1ATP4AATP4BCYP19A1 | |
| SCHEMBL11253700 | 0.91 | KMT2A (0.43) | NOS1HMOX1CYP19A1TP53MDM2 | |
| SCHEMBL11253896 | 0.90 | NOS1 (0.42) | NOS1HMOX1ATP4AATP4BCYP19A1 | |
| SCHEMBL11273449 | 0.90 | NOS1 (0.47) | NOS1HMOX1ATP4AATP4BQPCT | |
| SCHEMBL11261792 | 0.88 | NOS1 (0.44) | NOS1HMOX1ATP4AATP4BQPCT | |
| SCHEMBL11255295 | 0.87 | CYP19A1 (0.45) | QPCTCYP19A1KDM4EALDH1A1 | |
| SCHEMBL11267306 | 0.87 | NOS1 (0.46) | NOS1HMOX1ATP4AATP4BQPCT | |
| SCHEMBL11266807 | 0.86 | HMOX1 (0.45) | NOS1HMOX1CYP19A1KDM4EALDH1A1 | |
| SCHEMBL11266073 | 0.86 | CYP2A6 (0.45) | HMOX1CYP19A1TP53KDM4E | |
| SCHEMBL11261696 | 0.86 | TBXAS1 (0.42) | HMOX1QPCTCYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |