Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7155802 | 0.84 | ALOX15 (0.51) | ALOX15ALOX12SNCABACE1EGFR | |
| SCHEMBL385177 | 0.83 | GRIA2 (0.51) | ALOX15CYP1A2HSD17B10L3MBTL1 | |
| SCHEMBL385176 | 0.83 | GRIA2 (0.51) | ALOX15CYP1A2HSD17B10L3MBTL1 | |
| SCHEMBL28760029 | 0.80 | SNCA (0.47) | ALOX15ALOX12SNCABACE1EGFR | |
| SCHEMBL16969066 | 0.78 | SNCA (0.46) | ALOX15ALOX12SNCABACE1EGFR | |
| SCHEMBL28204498 | 0.78 | ALDH1A1 (0.55) | L3MBTL1 | |
| SCHEMBL9383321 | 0.78 | SNCA (0.48) | ALOX15ALOX12SNCABACE1EGFR | |
| SCHEMBL9281293 | 0.78 | PDK1 (0.55) | ALOX15ALOX12SNCABACE1EGFR | |
| SCHEMBL5929428 | 0.76 | ALDH1A1 (0.56) | ALOX15ALOX12SNCABACE1EGFR | |
| SCHEMBL28135355 | 0.76 | SNCA (0.47) | ALOX15ALOX12SNCABACE1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4305717-A | P-PHENYLENEDIAMINE OXIDIZING BASE AND COUPLER TO FORM INDAMINES | L'OREAL (FR) | 1981-12-15 | — | — | US | claimed |
| US-4152112-A | Dyeing composition for keratinic fibers containing paraphenylenediamines | L'OREAL (FR) | 1979-05-01 | — | — | US | claimed |
| US-4125367-A | FOR KERATINIC FIBERS | L'OREAL (FR) | 1978-11-14 | — | — | US | claimed |
| US-4329504-A | COUPLERS FOR DYES, HAIR DYES | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-05-11 | — | — | US | disclosed |
| US-4305717-A | P-PHENYLENEDIAMINE OXIDIZING BASE AND COUPLER TO FORM INDAMINES | L'OREAL (FR) | 1981-12-15 | — | — | US | disclosed |
| US-4277244-A | Dye compositions for keratinic fibers containing paraphenylenediamines | SOCIETE ANONYME DITE: L'OREAL (FR) | 1981-07-07 | — | — | US | disclosed |
| US-4259261-A | OXIDATION COLOR DYES FOR HAIR | L'OREAL (FR) | 1981-03-31 | — | — | US | disclosed |
| US-4152112-A | Dyeing composition for keratinic fibers containing paraphenylenediamines | L'OREAL (FR) | 1979-05-01 | — | — | US | disclosed |
| US-4125367-A | FOR KERATINIC FIBERS | L'OREAL (FR) | 1978-11-14 | — | — | US | disclosed |