Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.74 |
| ▸ | NPC1 | O15118 | 6/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | NAMPT | P43490 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.59 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16942610 | 0.87 | NPC1 (0.79) | EPHX1NPC1RAB9AMAPTKMT2A | |
| SCHEMBL4898509 | 0.85 | EPHX1 (1.00) | EPHX1NPC1RAB9AMAPTKMT2A | |
| SCHEMBL2831462 | 0.84 | NPC1 (0.77) | EPHX1NPC1RAB9AMAPTKMT2A | |
| SCHEMBL23747600 | 0.83 | RAB9A (0.61) | EPHX1NPC1RAB9AMAPTKMT2A | |
| SCHEMBL23747603 | 0.83 | RAB9A (0.61) | EPHX1NPC1RAB9AMAPTKMT2A | |
| SCHEMBL5853157 | 0.83 | NPC1 (0.88) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL3461361 | 0.83 | CA2 (0.68) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL8177097 | 0.83 | RAB9A (0.72) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL4117858 | 0.82 | RAB9A (0.67) | EPHX1NPC1RAB9AMAPTKMT2A | |
| SCHEMBL5998344 | 0.82 | MAOB (0.71) | NPC1RAB9AMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9284318-B2 | Protein kinase inhibitors | PHARMASCIENCE, INC. (CA) | 2016-03-15 | — | — | US | disclosed |
| US-9133186-B2 | Hetero ring-fused imidazole derivative having AMPK activating effect | SHIONOGI & CO., LTD. (JP) | 2015-09-15 | — | — | US | disclosed |
| US-20150210696-A1 | PROTEIN KINASE INHIBITORS | GB005, INC. | 2015-07-30 | — | — | US | disclosed |
| US-20130184240-A1 | HETERO RING-FUSED IMIDAZOLE DERIVATIVE HAVING AMPK ACTIVATING EFFECT | SHIONOGI & CO., LTD. (JP) | 2013-07-18 | — | — | US | disclosed |
| EP-0051466-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-05-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210696-A1 | PROTEIN KINASE INHIBITORS | PDGFRA, PDGFRB, KDR | EPHX1 3239/4885NPC1 4450/4885RAB9A 1817/4885 |
| US-20130184240-A1 | HETERO RING-FUSED IMIDAZOLE DERIVATIVE HAVING AMPK ACTIVATING EFFECT | PRKAA1, PRKAA2, PRKAG1 | EPHX1 4685/4885NPC1 2194/4885RAB9A 1895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.